Obstructive mechanical mitral valve thrombosis and gastric adenocarcinoma: A therapeutic dilemma.
Turk Kardiyol Dern Ars
; 48(8): 775-778, 2020 11.
Article
in En
| MEDLINE
| ID: mdl-33257607
ABSTRACT
Fibrinolysis is an option for the management of mechanical prosthetic valve thrombosis when surgery has prohibitive risks. Current guidelines suggest recombinant tissue plasminogen activator (not to exceed 100 mg) with unfractionated heparin. A low-dose (25 mg) alteplase regimen as treatment in patients with a high risk of bleeding warrants further research. This report describes the case of a 65-year-old woman with a history of mechanical prosthetic mitral valve replacement who was diagnosed with signet ring cell adenocarcinoma of the stomach and obstructive mechanical prosthetic thrombosis on echocardiogram. Details of challenging aspects of this case and the use of modified fibrinolytic therapy are provided.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stomach Neoplasms
/
Thrombosis
/
Heart Valve Prosthesis
/
Tissue Plasminogen Activator
/
Carcinoma, Signet Ring Cell
/
Fibrinolytic Agents
/
Mitral Valve
Type of study:
Guideline
Limits:
Aged
/
Female
/
Humans
Language:
En
Journal:
Turk Kardiyol Dern Ars
Journal subject:
CARDIOLOGIA
Year:
2020
Document type:
Article
Affiliation country:
Turkey