Antioxidant Activity of Silymarin in Microcystin-LR Cardiac and Pulmonary Induced Injuries on Mice.

Al-Hazmi, Ayman

Al-Hazmi, Ayman.

Pak J Biol Sci ; 23(11): 1369-1373, 2020 Jan.

Article in En | MEDLINE | ID: mdl-33274863

Subject(s)

Antioxidants/pharmacology; Heart Diseases/drug therapy; Lung/drug effects; Myocytes, Cardiac/drug effects; Oxidative Stress/drug effects; Pulmonary Fibrosis/drug therapy; Silymarin/pharmacology; Animals; Biomarkers/metabolism; Cardiotoxicity; Disease Models, Animal; Glutathione/metabolism; Heart Diseases/chemically induced; Heart Diseases/metabolism; Heart Diseases/pathology; Lipid Peroxidation/drug effects; Lung/metabolism; Lung/pathology; Male; Marine Toxins; Mice, Inbred BALB C; Microcystins; Myocytes, Cardiac/metabolism; Myocytes, Cardiac/pathology; Protein Carbonylation/drug effects; Protein Phosphatase 1/metabolism; Pulmonary Fibrosis/chemically induced; Pulmonary Fibrosis/metabolism; Pulmonary Fibrosis/pathology; Pyruvaldehyde/metabolism

Key words

Microcystin-LR; antioxidant; cyanobacteria; heart; lungs; oxidative stress; silymarin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Fibrosis / Silymarin / Oxidative Stress / Myocytes, Cardiac / Heart Diseases / Lung / Antioxidants Type of study: Prognostic_studies Limits: Animals Language: En Journal: Pak J Biol Sci Year: 2020 Document type: Article Country of publication: Pakistan

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