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Machine Learning of Hematopoietic Stem Cell Divisions from Paired Daughter Cell Expression Profiles Reveals Effects of Aging on Self-Renewal.
Arai, Fumio; Stumpf, Patrick S; Ikushima, Yoshiko M; Hosokawa, Kentaro; Roch, Aline; Lutolf, Matthias P; Suda, Toshio; MacArthur, Ben D.
Affiliation
  • Arai F; Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan. Electronic address: farai@med.kyushu-u.ac.jp.
  • Stumpf PS; Centre for Human Development, Stem Cells and Regeneration, University of Southampton, Southampton SO17 1BJ, UK; Joint Research Center for Computational Biomedicine, RWTH Aachen University, Aachen 52074, Germany.
  • Ikushima YM; Research Institute National Center for Global Health and Medicine, Tokyo, Japan.
  • Hosokawa K; Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
  • Roch A; Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences and School of Engineering, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne 1015, Switzerland.
  • Lutolf MP; Laboratory of Stem Cell Bioengineering, Institute of Bioengineering, School of Life Sciences and School of Engineering, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne 1015, Switzerland.
  • Suda T; Cancer Science Institute, National University of Singapore, 14 Medical Drive, MD6, Singapore 117599, Singapore.
  • MacArthur BD; Centre for Human Development, Stem Cells and Regeneration, University of Southampton, Southampton SO17 1BJ, UK; Institute for Life Sciences, University of Southampton, Southampton SO17 1BJ, UK; Mathematical Sciences, University of Southampton, Southampton SO17 1BJ, UK. Electronic address: bdm@soton.
Cell Syst ; 11(6): 640-652.e5, 2020 12 16.
Article in En | MEDLINE | ID: mdl-33296684
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Cell Differentiation / Cell Division / Machine Learning Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Syst Year: 2020 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Cell Differentiation / Cell Division / Machine Learning Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Syst Year: 2020 Document type: Article Country of publication: United States