Application of Random Forest and data integration identifies three dysregulated genes and enrichment of Central Carbon Metabolism pathway in Oral Cancer.

Mukhopadhyay, Srija; Ghosh, Sahana; Das, Debodipta; Arun, P; Roy, Bidyut; Biswas, Nidhan K; Maitra, Arindam; Majumder, Partha P

Mukhopadhyay, Srija; Ghosh, Sahana; Das, Debodipta; Arun, P; Roy, Bidyut; Biswas, Nidhan K; Maitra, Arindam; Majumder, Partha P.

Affiliation

Mukhopadhyay S; National Institute of Biomedical Genomics, Kalyani, 741251, India.
Ghosh S; National Institute of Biomedical Genomics, Kalyani, 741251, India.
Das D; National Institute of Biomedical Genomics, Kalyani, 741251, India.
Arun P; Tata Medical Centre, Kolkata, India.
Roy B; Indian Statistical Institute, Kolkata, India.
Biswas NK; National Institute of Biomedical Genomics, Kalyani, 741251, India.
Maitra A; National Institute of Biomedical Genomics, Kalyani, 741251, India.
Majumder PP; National Institute of Biomedical Genomics, Kalyani, 741251, India. ppm1@nibmg.ac.in.

BMC Cancer ; 20(1): 1219, 2020 Dec 14.

Article in En | MEDLINE | ID: mdl-33317464

Subject(s)

Biomarkers, Tumor/metabolism; Carbon/metabolism; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Mouth Neoplasms/pathology; Neoplastic Stem Cells/pathology; Biomarkers, Tumor/genetics; Carcinoma, Squamous Cell/genetics; Carcinoma, Squamous Cell/metabolism; Carcinoma, Squamous Cell/pathology; Humans; Mouth Neoplasms/genetics; Mouth Neoplasms/metabolism; Neoplasm Recurrence, Local/genetics; Neoplasm Recurrence, Local/metabolism; Neoplasm Recurrence, Local/pathology; Neoplastic Stem Cells/metabolism; Prognosis; Promoter Regions, Genetic

Key words

Epigenomic; Gingivo-buccal oral cancer; Integrative analysis; Random Forest; Transcriptomic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Mouth Neoplasms / Carbon / Biomarkers, Tumor / Gene Expression Regulation, Neoplastic / DNA Methylation / Epigenesis, Genetic Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2020 Document type: Article Affiliation country: India Country of publication: United kingdom

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