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Secoiridoid Glucosides and Anti-Inflammatory Constituents from the Stem Bark of Fraxinus chinensis.
Chang, Hao-Chiun; Wang, Shih-Wei; Chen, Chin-Yen; Hwang, Tsong-Long; Cheng, Ming-Jen; Sung, Ping-Jyun; Liao, Kuang-Wen; Chen, Jih-Jung.
Affiliation
  • Chang HC; Department of Orthopaedics, MacKay Memorial Hospital, Taipei 10449, Taiwan.
  • Wang SW; Ph.D. Degree Program of Biomedical Science and Engineering, National Chiao Tung University, Hsinchu City 30068, Taiwan.
  • Chen CY; Department of Medicine, MacKay Medical College, New Taipei City 25242, Taiwan.
  • Hwang TL; Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
  • Cheng MJ; Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 90741, Taiwan.
  • Sung PJ; Graduate Institute of Natural Products, School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan 33303, Taiwan.
  • Liao KW; Research Center for Food and Cosmetic Safety, Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 33303, Taiwan.
  • Chen JJ; Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Molecules ; 25(24)2020 Dec 14.
Article in En | MEDLINE | ID: mdl-33327368
Subject(s)
Anti-Inflammatory Agents/pharmacology; Fraxinus/chemistry; Gene Expression Regulation/drug effects; Iridoid Glucosides/pharmacology; Plant Bark/chemistry; Animals; Anti-Inflammatory Agents/chemistry; Anti-Inflammatory Agents/classification; Anti-Inflammatory Agents/isolation & purification; Cytochalasin B/antagonists & inhibitors; Cytochalasin B/pharmacology; Gene Expression Regulation/immunology; Humans; Interleukin-6/genetics; Interleukin-6/immunology; Iridoid Glucosides/chemistry; Iridoid Glucosides/classification; Iridoid Glucosides/isolation & purification; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors/genetics; Kruppel-Like Transcription Factors/immunology; Leukocyte Elastase/immunology; Leukocyte Elastase/metabolism; Lipopolysaccharides/antagonists & inhibitors; Lipopolysaccharides/pharmacology; MAP Kinase Kinase 4/genetics; MAP Kinase Kinase 4/immunology; Mice; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine/antagonists & inhibitors; N-Formylmethionine Leucyl-Phenylalanine/pharmacology; NF-KappaB Inhibitor alpha/genetics; NF-KappaB Inhibitor alpha/immunology; Neutrophils/cytology; Neutrophils/drug effects; Neutrophils/immunology; Nitric Oxide/antagonists & inhibitors; Nitric Oxide/metabolism; Plant Extracts/chemistry; Primary Cell Culture; RAW 264.7 Cells; Structure-Activity Relationship; Superoxides/antagonists & inhibitors; Superoxides/metabolism; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/immunology; p38 Mitogen-Activated Protein Kinases/genetics; p38 Mitogen-Activated Protein Kinases/immunology
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Plant Bark / Fraxinus / Iridoid Glucosides / Anti-Inflammatory Agents Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2020 Document type: Article Affiliation country: Taiwan Country of publication: Switzerland
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Plant Bark / Fraxinus / Iridoid Glucosides / Anti-Inflammatory Agents Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2020 Document type: Article Affiliation country: Taiwan Country of publication: Switzerland