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An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex.
Hammel, Michal; Rashid, Ishtiaque; Sverzhinsky, Aleksandr; Pourfarjam, Yasin; Tsai, Miaw-Sheue; Ellenberger, Tom; Pascal, John M; Kim, In-Kwon; Tainer, John A; Tomkinson, Alan E.
Affiliation
  • Hammel M; Molecular Biophysics & Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  • Rashid I; Departments of Internal Medicine, Molecular Genetics & Microbiology and the University of New Mexico Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM 87131, USA.
  • Sverzhinsky A; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec, Canada.
  • Pourfarjam Y; Department of Chemistry, University of Cincinnati, 301 Clifton Ct, Cincinnati, OH 45221, USA.
  • Tsai MS; Molecular Biophysics & Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  • Ellenberger T; Department of Biochemistry, Washington University, St. Louis, MO, USA.
  • Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec, Canada.
  • Kim IK; Department of Chemistry, University of Cincinnati, 301 Clifton Ct, Cincinnati, OH 45221, USA.
  • Tainer JA; Departments of Cancer Biology and Molecular & Cellular Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Tomkinson AE; Departments of Internal Medicine, Molecular Genetics & Microbiology and the University of New Mexico Comprehensive Cancer Center, University of New Mexico, Albuquerque, NM 87131, USA.
Nucleic Acids Res ; 49(1): 306-321, 2021 01 11.
Article in En | MEDLINE | ID: mdl-33330937
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Repair / DNA Ligase ATP / X-ray Repair Cross Complementing Protein 1 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Repair / DNA Ligase ATP / X-ray Repair Cross Complementing Protein 1 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom