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Combinatorial treatment with menin and FLT3 inhibitors induces complete remission in AML models with activating FLT3 mutations.
Miao, Hongzhi; Kim, EunGi; Chen, Dong; Purohit, Trupta; Kempinska, Katarzyna; Ropa, James; Klossowski, Szymon; Trotman, Winifred; Danet-Desnoyers, Gwenn; Cierpicki, Tomasz; Grembecka, Jolanta.
Affiliation
  • Miao H; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Kim E; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Chen D; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Purohit T; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Kempinska K; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Ropa J; Department of Microbiology and Immunology, School of Medicine, Indiana University, Indianapolis, IN; and.
  • Klossowski S; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Trotman W; Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Danet-Desnoyers G; Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
  • Cierpicki T; Department of Pathology, University of Michigan, Ann Arbor, MI.
  • Grembecka J; Department of Pathology, University of Michigan, Ann Arbor, MI.
Blood ; 136(25): 2958-2963, 2020 12 17.
Article in En | MEDLINE | ID: mdl-33331926
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Antineoplastic Combined Chemotherapy Protocols / Proto-Oncogene Proteins / Fms-Like Tyrosine Kinase 3 / Models, Biological / Mutation Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: Blood Year: 2020 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Antineoplastic Combined Chemotherapy Protocols / Proto-Oncogene Proteins / Fms-Like Tyrosine Kinase 3 / Models, Biological / Mutation Type of study: Clinical_trials Limits: Female / Humans / Male Language: En Journal: Blood Year: 2020 Document type: Article