Multisystem Inflammatory Syndrome in Children in February 2020 and Implications of Genomic Sequencing for SARS-CoV-2.
J Pediatric Infect Dis Soc
; 10(5): 695-697, 2021 May 28.
Article
in En
| MEDLINE
| ID: mdl-33336251
ABSTRACT
Multisystem inflammatory syndrome in children (MIS-C) is a newly recognized disease process that can complicate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We present what we believe to be the earliest case of MIS-C, occurring in February 2020. Our patient's SARS-CoV-2 infection was caused by an emerging lineage with the D614G variant in the spike protein. This lineage would subsequently become the predominant cause of SARS-CoV-2 outbreaks in Europe and the United States where MIS-C was first described.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Genome, Viral
/
Systemic Inflammatory Response Syndrome
/
Spike Glycoprotein, Coronavirus
/
SARS-CoV-2
/
COVID-19
Limits:
Child
/
Humans
/
Male
Language:
En
Journal:
J Pediatric Infect Dis Soc
Year:
2021
Document type:
Article
Affiliation country:
United States