Boric Acid-Fueled ATP Synthesis by Fo F1 ATP Synthase Reconstituted in a Supramolecular Architecture.
Angew Chem Int Ed Engl
; 60(14): 7617-7620, 2021 03 29.
Article
in En
| MEDLINE
| ID: mdl-33369011
ABSTRACT
Significant strides toward producing biochemical fuels have been achieved by mimicking natural oxidative and photosynthetic phosphorylation. Here, different from these strategies, we explore boric acid as a fuel for tuneable synthesis of energy-storing molecules in a cell-like supramolecular architecture. Specifically, a proton locked in boric acid is released in a modulated fashion by the choice of polyols. As a consequence, controlled proton gradients across the lipid membrane are established to drive ATP synthase embedded in the biomimetic architecture, which facilitates tuneable ATP production. This strategy paves a unique route to achieve highly efficient bioenergy conversion, holding broad applications in synthesis and devices that require biochemical fuels.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Boric Acids
/
Recombinant Fusion Proteins
/
Adenosine Triphosphate
/
Fluorescent Dyes
/
Membrane Lipids
Language:
En
Journal:
Angew Chem Int Ed Engl
Year:
2021
Document type:
Article
Affiliation country:
China