Diversity, Bioactivity Profiling and Untargeted Metabolomics of the Cultivable Gut Microbiota of <i>Ciona intestinalis</i>.

Utermann, Caroline; Echelmeyer, Vivien A; Oppong-Danquah, Ernest; Blümel, Martina; Tasdemir, Deniz

Diversity, Bioactivity Profiling and Untargeted Metabolomics of the Cultivable Gut Microbiota of Ciona intestinalis.

Utermann, Caroline; Echelmeyer, Vivien A; Oppong-Danquah, Ernest; Blümel, Martina; Tasdemir, Deniz.

Affiliation

Utermann C; GEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany.
Echelmeyer VA; GEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany.
Oppong-Danquah E; GEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany.
Blümel M; GEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany.
Tasdemir D; GEOMAR Centre for Marine Biotechnology (GEOMAR-Biotech), Research Unit Marine Natural Products Chemistry, GEOMAR Helmholtz Centre for Ocean Research Kiel, Am Kiel-Kanal 44, 24106 Kiel, Germany.

Mar Drugs ; 19(1)2020 Dec 24.

Article in En | MEDLINE | ID: mdl-33374243

Subject(s)

Bacteria/metabolism; Ciona intestinalis/microbiology; Fungi/metabolism; Gastrointestinal Microbiome; Metabolomics; Animals; Anti-Bacterial Agents/metabolism; Anti-Bacterial Agents/pharmacology; Antifungal Agents/metabolism; Antifungal Agents/pharmacology; Antineoplastic Agents/metabolism; Antineoplastic Agents/pharmacology; Bacteria/classification; Bacteria/isolation & purification; Chromatography, Liquid; Fungi/classification; Fungi/isolation & purification; Tandem Mass Spectrometry

Key words

Ciona intestinalis; anticancer activity; antimicrobial activity; feature-based molecular networking; gut-associated microbiota; in silico MS/MS-based dereplication; marine natural products; tunicate; untargeted metabolomics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Ciona intestinalis / Metabolomics / Gastrointestinal Microbiome / Fungi Limits: Animals Language: En Journal: Mar Drugs Journal subject: BIOLOGIA / FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: Germany Country of publication: Switzerland

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