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Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Robert Hollingsworth, L; David, Liron; Li, Yang; Griswold, Andrew R; Ruan, Jianbin; Sharif, Humayun; Fontana, Pietro; Orth-He, Elizabeth L; Fu, Tian-Min; Bachovchin, Daniel A; Wu, Hao.
Affiliation
  • Robert Hollingsworth L; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
  • David L; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Li Y; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, 02115, USA.
  • Griswold AR; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
  • Ruan J; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Sharif H; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Fontana P; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.
  • Orth-He EL; Pharmacology Program, Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Fu TM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, 02115, USA.
  • Bachovchin DA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Wu H; Department of Immunology, University of Connecticut Health Center, Farmington, CT, USA.
Nat Commun ; 12(1): 189, 2021 01 08.
Article in En | MEDLINE | ID: mdl-33420033
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ankyrins / Adaptor Proteins, Signal Transducing / Apoptosis Regulatory Proteins / CARD Signaling Adaptor Proteins / Inflammasomes / Neoplasm Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ankyrins / Adaptor Proteins, Signal Transducing / Apoptosis Regulatory Proteins / CARD Signaling Adaptor Proteins / Inflammasomes / Neoplasm Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom