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Nanocarrier vaccines for SARS-CoV-2.
Machhi, Jatin; Shahjin, Farah; Das, Srijanee; Patel, Milankumar; Abdelmoaty, Mai Mohamed; Cohen, Jacob D; Singh, Preet Amol; Baldi, Ashish; Bajwa, Neha; Kumar, Raj; Vora, Lalit K; Patel, Tapan A; Oleynikov, Maxim D; Soni, Dhruvkumar; Yeapuri, Pravin; Mukadam, Insiya; Chakraborty, Rajashree; Saksena, Caroline G; Herskovitz, Jonathan; Hasan, Mahmudul; Oupicky, David; Das, Suvarthi; Donnelly, Ryan F; Hettie, Kenneth S; Chang, Linda; Gendelman, Howard E; Kevadiya, Bhavesh D.
Affiliation
  • Machhi J; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Shahjin F; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Das S; Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Patel M; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Abdelmoaty MM; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, NE 68198, USA; Therapeutic Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Giza, Egypt.
  • Cohen JD; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Singh PA; Department of Pharmaceutical Sciences & Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India.
  • Baldi A; Department of Pharmaceutical Sciences & Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India.
  • Bajwa N; Department of Pharmaceutical Sciences & Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India.
  • Kumar R; Center for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Vora LK; School of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, United Kingdom.
  • Patel TA; Department of Biological Sciences, P. D. Patel Institute of Applied Sciences (PDPIAS), Charotar University of Science and Technology (CHARUSAT), Changa, Anand 388421, Gujarat, India.
  • Oleynikov MD; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Soni D; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, NE 68198, USA.
  • Yeapuri P; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Mukadam I; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, NE 68198, USA.
  • Chakraborty R; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Saksena CG; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Herskovitz J; Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
  • Hasan M; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, NE 68198, USA.
  • Oupicky D; Center for Drug Delivery and Nanomedicine, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
  • Das S; Department of Medicine, Stanford Medical School, Stanford University, Palo Alto, CA 94304, USA.
  • Donnelly RF; School of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, United Kingdom.
  • Hettie KS; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Department of Otolaryngology - Head & Neck Surgery, Stanford University, Palo Alto, CA 94304, USA.
  • Chang L; Departments of Diagnostic Radiology & Nuclear Medicine, and Neurology, University of Maryland, School of Medicine, Baltimore, MD 21201, USA.
  • Gendelman HE; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA; Department of Pathology and Microbiology, College of Medicine, University of Nebraska Medical Center, NE 68198, USA; Department of Pharmaceutical Sciences, College of
  • Kevadiya BD; Department of Pharmacology and Experimental Neuroscience, College of Medicine, University of Nebraska Medical Center, NE 68198, USA.
Adv Drug Deliv Rev ; 171: 215-239, 2021 04.
Article in En | MEDLINE | ID: mdl-33428995
The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death associated with substantive social, economic and societal impacts. Treatments rely on re-purposed antivirals and immune modulatory agents focusing on attenuating the acute respiratory distress syndrome. No curative therapies exist. Vaccines remain the best hope for disease control and the principal global effort to end the pandemic. Herein, we summarize those developments with a focus on the role played by nanocarrier delivery.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Carriers / Nanocapsules / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Limits: Animals / Humans Language: En Journal: Adv Drug Deliv Rev Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2021 Document type: Article Affiliation country: United States Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Carriers / Nanocapsules / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Limits: Animals / Humans Language: En Journal: Adv Drug Deliv Rev Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2021 Document type: Article Affiliation country: United States Country of publication: Netherlands