The combination of atorvastatin with silymarin enhances hypolipidemic, antioxidant and anti-inflammatory effects in a rat model of metabolic syndrome.

Marková, I; Malínská, H; Hüttl, M; Miklánková, D; Oliyarnyk, O; Poruba, M; Rácová, Z; Kazdová, L; Vecera, R

Marková, I; Malínská, H; Hüttl, M; Miklánková, D; Oliyarnyk, O; Poruba, M; Rácová, Z; Kazdová, L; Vecera, R.

Affiliation

Marková I; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic. irena.markova@ikem.cz.

Physiol Res ; 70(1): 33-43, 2021 03 17.

Article in En | MEDLINE | ID: mdl-33453720

Subject(s)

Atorvastatin/adverse effects; Diabetes Mellitus, Type 2/drug therapy; Hyperlipidemias/drug therapy; Metabolic Syndrome/drug therapy; Oxidative Stress/drug effects; Silymarin/pharmacology; Triglycerides/blood; Animals; Anticholesteremic Agents/adverse effects; Antioxidants/pharmacology; Diabetes Mellitus, Type 2/chemically induced; Diabetes Mellitus, Type 2/pathology; Disease Models, Animal; Drug Therapy, Combination; Hypercholesterolemia/blood; Inflammation/drug therapy; Male; Metabolic Syndrome/genetics; Metabolic Syndrome/pathology; Rats

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Silymarin / Triglycerides / Oxidative Stress / Metabolic Syndrome / Diabetes Mellitus, Type 2 / Atorvastatin / Hyperlipidemias Limits: Animals Language: En Journal: Physiol Res Journal subject: FISIOLOGIA Year: 2021 Document type: Article Affiliation country: Czech Republic

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