Piecing together the Pediatric Brain Tumor Puzzle.
Trends Genet
; 37(3): 204-206, 2021 03.
Article
in En
| MEDLINE
| ID: mdl-33455817
ABSTRACT
A recent study by Petralia et al. of 218 pediatric brain tumors across seven different entities applied an integrated approach incorporating proteomics, phosphoproteomics, whole-genome sequencing, and RNA sequencing. This elegant study unveiled new signaling pathways, the composition of tumor microenvironments, and functional effects of copy number variants and somatic mutations.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pediatrics
/
Brain Neoplasms
/
Proteomics
/
Neoplasm Proteins
Limits:
Child
/
Humans
Language:
En
Journal:
Trends Genet
Journal subject:
GENETICA
Year:
2021
Document type:
Article