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Piecing together the Pediatric Brain Tumor Puzzle.
Nör, Carolina; Ramaswamy, Vijay.
Affiliation
  • Nör C; Programme in Developmental and Stem Cell Biology, Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON, Canada. Electronic address: carolina.nor@sickkids.ca.
  • Ramaswamy V; Programme in Developmental and Stem Cell Biology, Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON, Canada; Division of Haematology/Oncology, Hospital for Sick Children, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. Electronic address: vijay.ramaswamy@sickkids.ca.
Trends Genet ; 37(3): 204-206, 2021 03.
Article in En | MEDLINE | ID: mdl-33455817
ABSTRACT
A recent study by Petralia et al. of 218 pediatric brain tumors across seven different entities applied an integrated approach incorporating proteomics, phosphoproteomics, whole-genome sequencing, and RNA sequencing. This elegant study unveiled new signaling pathways, the composition of tumor microenvironments, and functional effects of copy number variants and somatic mutations.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pediatrics / Brain Neoplasms / Proteomics / Neoplasm Proteins Limits: Child / Humans Language: En Journal: Trends Genet Journal subject: GENETICA Year: 2021 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pediatrics / Brain Neoplasms / Proteomics / Neoplasm Proteins Limits: Child / Humans Language: En Journal: Trends Genet Journal subject: GENETICA Year: 2021 Document type: Article