Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex.

Hirst, Jennifer; Hesketh, Geoffrey G; Gingras, Anne-Claude; Robinson, Margaret S

Hirst, Jennifer; Hesketh, Geoffrey G; Gingras, Anne-Claude; Robinson, Margaret S.

Affiliation

Hirst J; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Hesketh GG; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.
Gingras AC; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.
Robinson MS; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

J Cell Biol ; 220(2)2021 02 01.

Article in En | MEDLINE | ID: mdl-33464297

Subject(s)

Adaptor Proteins, Vesicular Transport/metabolism; Carrier Proteins/metabolism; Monomeric GTP-Binding Proteins/metabolism; Multiprotein Complexes/metabolism; Phosphatidylinositol Phosphates/metabolism; Proteins/metabolism; Carrier Proteins/chemistry; Endosomes/metabolism; HEK293 Cells; HeLa Cells; Humans; Lysosomes/metabolism; Mechanistic Target of Rapamycin Complex 1/metabolism; Models, Biological; Nucleotides/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Protein Domains

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Carrier Proteins / Phosphatidylinositol Phosphates / Monomeric GTP-Binding Proteins / Adaptor Proteins, Vesicular Transport / Multiprotein Complexes Limits: Humans Language: En Journal: J Cell Biol Year: 2021 Document type: Article Affiliation country: United kingdom Country of publication: United States

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