Effects of transfusion load and suction pressure on renal function in intraoperative salvage autotransfusion.
Braz J Med Biol Res
; 54(3): e10292, 2021.
Article
in En
| MEDLINE
| ID: mdl-33470391
ABSTRACT
Although some investigations have been performed to determine the effects of transfusion load and suction pressure on renal function during intraoperative salvage autotransfusion, the precise threshold is still undetermined. A total of 625 patients undergoing surgery with the Continuous AutoTransfusion System (CATSplus) were enrolled and divided into groups according to the utilized suction pressure and transfusion volume. Plasma free hemoglobin (FHB) and creatinine clearance (CCr) were assayed to indicate the renal function. Both 0.03 MPa suction (≥4-unit load) and >5 units transfusion changed the levels of FHB and CCr significantly when measured 24 h post-operation compared to pre-operation. Under 0.02 MPa suction (≥4-unit load), the alteration of FHB and CCr returned to normal after 24 h. Under 3 units transfusion, the levels of FHB and CCr at 6 and 12 h post-operation changed significantly compared to pre-operation (P<0.05 or P<0.01, respectively), and this alteration could be restored to normal at 72 h post-operation. After an exhaustive investigation, less than 4 units transfusion and less than 0.03 MPa suction pressure are recommended for intraoperative salvage autotransfusion.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Blood Transfusion
/
Blood Transfusion, Autologous
Limits:
Humans
Language:
En
Journal:
Braz J Med Biol Res
Year:
2021
Document type:
Article
Affiliation country:
China