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GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers.
Li, Yapeng; Gao, Junfeng; Kamran, Mohammad; Harmacek, Laura; Danhorn, Thomas; Leach, Sonia M; O'Connor, Brian P; Hagman, James R; Huang, Hua.
Affiliation
  • Li Y; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
  • Gao J; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
  • Kamran M; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
  • Harmacek L; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, 80206, USA.
  • Danhorn T; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, 80206, USA.
  • Leach SM; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
  • O'Connor BP; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, 80206, USA.
  • Hagman JR; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, 80206, USA.
  • Huang H; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
Nat Commun ; 12(1): 494, 2021 01 21.
Article in En | MEDLINE | ID: mdl-33479210
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enhancer Elements, Genetic / Chromatin Assembly and Disassembly / GATA2 Transcription Factor / Mast Cells / Antigens Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enhancer Elements, Genetic / Chromatin Assembly and Disassembly / GATA2 Transcription Factor / Mast Cells / Antigens Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United kingdom