Integrin Linked Kinase (ILK) and its Role in Liver Pathobiology.
Gene Expr
; 20(3): 201-207, 2021 06 11.
Article
in En
| MEDLINE
| ID: mdl-33482930
ABSTRACT
Integrin linked kinase (ILK) is a vital signaling protein ubiquitously expressed throughout the body. It binds to intracellular integrins to help promote signaling related to cell adhesion, apoptosis, proliferation, migration, and a plethora of other common cellular functions. In this review, ILKs role in the liver is detailed. Studies have shown ILK to be a major participant in hepatic ECM organization, liver regeneration, insulin resistance, and hepatocellular carcinoma.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Protein Serine-Threonine Kinases
/
Liver
/
Liver Diseases
Limits:
Animals
/
Humans
Language:
En
Journal:
Gene Expr
Journal subject:
BIOLOGIA MOLECULAR
Year:
2021
Document type:
Article