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Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer.
Steele, Nina G; Biffi, Giulia; Kemp, Samantha B; Zhang, Yaqing; Drouillard, Donovan; Syu, LiJyun; Hao, Yuan; Oni, Tobiloba E; Brosnan, Erin; Elyada, Ela; Doshi, Abhishek; Hansma, Christa; Espinoza, Carlos; Abbas, Ahmed; The, Stephanie; Irizarry-Negron, Valerie; Halbrook, Christopher J; Franks, Nicole E; Hoffman, Megan T; Brown, Kristee; Carpenter, Eileen S; Nwosu, Zeribe C; Johnson, Craig; Lima, Fatima; Anderson, Michelle A; Park, Youngkyu; Crawford, Howard C; Lyssiotis, Costas A; Frankel, Timothy L; Rao, Arvind; Bednar, Filip; Dlugosz, Andrzej A; Preall, Jonathan B; Tuveson, David A; Allen, Benjamin L; Pasca di Magliano, Marina.
Affiliation
  • Steele NG; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan.
  • Biffi G; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, England, United Kingdom.
  • Kemp SB; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Zhang Y; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Drouillard D; Molecular and Cellular Pathology Graduate Program, University of Michigan, Ann Arbor, Michigan.
  • Syu L; Department of Surgery, University of Michigan, Ann Arbor, Michigan.
  • Hao Y; Department of Surgery, University of Michigan, Ann Arbor, Michigan.
  • Oni TE; Department of Dermatology, University of Michigan, Ann Arbor, Michigan.
  • Brosnan E; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Elyada E; Applied Bioinformatics Laboratories, NYU Grossman School of Medicine, New York, New York.
  • Doshi A; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Hansma C; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Espinoza C; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Abbas A; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • The S; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Irizarry-Negron V; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Halbrook CJ; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Franks NE; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Hoffman MT; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan.
  • Brown K; Department of Surgery, University of Michigan, Ann Arbor, Michigan.
  • Carpenter ES; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan.
  • Nwosu ZC; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.
  • Johnson C; Department of Surgery, University of Michigan, Ann Arbor, Michigan.
  • Lima F; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.
  • Anderson MA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan.
  • Park Y; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.
  • Crawford HC; Department of Surgery, University of Michigan, Ann Arbor, Michigan.
  • Lyssiotis CA; Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Frankel TL; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.
  • Rao A; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan.
  • Bednar F; Department of Surgery, University of Michigan, Ann Arbor, Michigan.
  • Dlugosz AA; Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Preall JB; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Tuveson DA; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Allen BL; Molecular and Cellular Pathology Graduate Program, University of Michigan, Ann Arbor, Michigan.
  • Pasca di Magliano M; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.
Clin Cancer Res ; 27(7): 2023-2037, 2021 04 01.
Article in En | MEDLINE | ID: mdl-33495315

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Carcinoma, Pancreatic Ductal / Hedgehog Proteins / Cancer-Associated Fibroblasts Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2021 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Carcinoma, Pancreatic Ductal / Hedgehog Proteins / Cancer-Associated Fibroblasts Limits: Animals / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2021 Document type: Article Country of publication: United States