SEOM clinical guidelines for the treatment of malignant pleural mesothelioma (2020).
Clin Transl Oncol
; 23(5): 980-987, 2021 May.
Article
in En
| MEDLINE
| ID: mdl-33538989
ABSTRACT
Mesothelioma is a rare and aggressive tumour with dismal prognosis arising in the pleura and associated with asbestos exposure. Its incidence is on the rise worldwide. In selected patients with early-stage MPM, a maximal surgical cytoreduction in combination with additional antitumour treatment may be considered in selected patients assessed by a multidisciplinary tumor board. In patients with unresectable or advanced MPM, chemotherapy with platinum plus pemetrexed is the standard of care. Currently, no standard salvage therapy has been approved yet, but second-line chemotherapy with vinorelbine or gemcitabine is commonly used. Novel therapeutic approaches based on dual immunotherapy or chemotherapy plus immunotherapy demonstrated promising survival benefit and will probably be incorporated in the future.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pleural Neoplasms
/
Mesothelioma, Malignant
Type of study:
Etiology_studies
/
Guideline
/
Prognostic_studies
Limits:
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Clin Transl Oncol
Year:
2021
Document type:
Article
Affiliation country:
Spain