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Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484.
Sillen, Machteld; Miyata, Toshio; Vaughan, Douglas E; Strelkov, Sergei V; Declerck, Paul J.
Affiliation
  • Sillen M; Laboratory for Therapeutic and Diagnostic Antibodies, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, B-3000 Leuven, Belgium.
  • Miyata T; Department of Molecular Medicine and Therapy, United Centers for Advanced Research and Translational Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8577, Japan.
  • Vaughan DE; Department of Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Strelkov SV; Laboratory for Biocrystallography, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, B-3000 Leuven, Belgium.
  • Declerck PJ; Laboratory for Therapeutic and Diagnostic Antibodies, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, B-3000 Leuven, Belgium.
Int J Mol Sci ; 22(3)2021 Feb 02.
Article in En | MEDLINE | ID: mdl-33540702
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasminogen Activator Inhibitor 1 Limits: Humans Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Belgium
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasminogen Activator Inhibitor 1 Limits: Humans Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Belgium