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Bitter taste receptor T2R14 detects quorum sensing molecules from cariogenic Streptococcus mutans and mediates innate immune responses in gingival epithelial cells.
Medapati, Manoj Reddy; Singh, Nisha; Bhagirath, Anjali Yadav; Duan, Kangmin; Triggs-Raine, Barbara; Batista, Eraldo L; Chelikani, Prashen.
Affiliation
  • Medapati MR; Manitoba Chemosensory Biology Research Group and Department of Oral Biology, Dr. Gerald Niznick College of Dentistry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
  • Singh N; Manitoba Chemosensory Biology Research Group and Department of Oral Biology, Dr. Gerald Niznick College of Dentistry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
  • Bhagirath AY; Manitoba Chemosensory Biology Research Group and Department of Oral Biology, Dr. Gerald Niznick College of Dentistry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
  • Duan K; Children's Hospital Research Institute of Manitoba (CHRIM), University of Manitoba, Winnipeg, Canada.
  • Triggs-Raine B; Manitoba Chemosensory Biology Research Group and Department of Oral Biology, Dr. Gerald Niznick College of Dentistry, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.
  • Batista EL; Children's Hospital Research Institute of Manitoba (CHRIM), University of Manitoba, Winnipeg, Canada.
  • Chelikani P; Children's Hospital Research Institute of Manitoba (CHRIM), University of Manitoba, Winnipeg, Canada.
FASEB J ; 35(3): e21375, 2021 03.
Article in En | MEDLINE | ID: mdl-33559200
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptococcus mutans / Bacterial Proteins / Receptors, G-Protein-Coupled / Quorum Sensing / Host-Pathogen Interactions / Gingiva Type of study: Prognostic_studies Limits: Humans Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2021 Document type: Article Affiliation country: Canada
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptococcus mutans / Bacterial Proteins / Receptors, G-Protein-Coupled / Quorum Sensing / Host-Pathogen Interactions / Gingiva Type of study: Prognostic_studies Limits: Humans Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2021 Document type: Article Affiliation country: Canada