Cytotoxic activity of high dose ascorbic acid is enhanced by 2-deoxy-d-glucose in glycolytic melanoma cells.

Hill-Mündel, Katharina; Nohr, Donatus

Hill-Mündel, Katharina; Nohr, Donatus.

Affiliation

Hill-Mündel K; Institute of Nutritional Sciences, University of Hohenheim, Garbenstraße 30, 70599, Stuttgart, Germany. Electronic address: Katharina_Hill@uni-hohenheim.de.
Nohr D; Institute of Nutritional Sciences, University of Hohenheim, Garbenstraße 30, 70599, Stuttgart, Germany. Electronic address: donatus.nohr@uni-hohenheim.de.

Biochem Biophys Res Commun ; 546: 90-96, 2021 03 26.

Article in En | MEDLINE | ID: mdl-33578294

Subject(s)

Ascorbic Acid/pharmacology; Deoxyglucose/pharmacology; Glucose/metabolism; Glycolysis; Melanoma/metabolism; Melanoma/pathology; Cell Line, Tumor; Cell Proliferation/drug effects; Humans; Hydrogen Peroxide/metabolism; Lactic Acid/metabolism; Pyruvic Acid/metabolism

Key words

2-Deoxy-d-glucose; Ascorbic acid; Cancer; Glycolysis; Hydrogen peroxide; Lactate; Pharmacology; Pyruvate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ascorbic Acid / Deoxyglucose / Glucose / Glycolysis / Melanoma Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2021 Document type: Article Country of publication: United States

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