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Outcomes of acute hepatitis B virus (HBV) in HIV infection with and without HBV-active antiretroviral therapy.
Falade-Nwulia, Oluwaseun; Seaberg, Eric C; Snider, Anna E; Rinaldo, Charles R; Wolinsky, Steven M; Witt, Mallory D; Thio, Chloe L.
Affiliation
  • Falade-Nwulia O; Johns Hopkins University, Baltimore, Maryland.
  • Seaberg EC; Johns Hopkins University, Baltimore, Maryland.
  • Snider AE; Johns Hopkins University, Baltimore, Maryland.
  • Rinaldo CR; Departments of Pathology and Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Wolinsky SM; Department of Medicine, Feinberg School of Medicine, Northwestern University Chicago, Chicago, Illinois.
  • Witt MD; Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
  • Thio CL; Johns Hopkins University, Baltimore, Maryland.
AIDS ; 35(6): 991-993, 2021 05 01.
Article in En | MEDLINE | ID: mdl-33587444
Men with acute hepatitis B virus (HBV) infection in the Multicenter AIDS Cohort Study from 1985 to 2013 had serological testing to determine proportions with HBV recovery or chronic hepatitis B (CHB). A similar proportion of men without human immunodeficiency virus (HIV) and men with HIV receiving HBV-active antiretroviral therapy (ART) developed CHB [8.2%, 95% confidence interval (CI) 3.8-15.0% vs. 7.7%, 95% CI 2.00-36.0%]. In contrast, 17.5% (95% CI 8.7-29.9%) of men living with HIV, not on HBV-active ART developed CHB. HBV-active ART protects against developing CHB.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Hepatitis B, Chronic / Hepatitis B Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Humans / Male Language: En Journal: AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2021 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / Hepatitis B, Chronic / Hepatitis B Type of study: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Humans / Male Language: En Journal: AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2021 Document type: Article Country of publication: United kingdom