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Tricyclic-Carbocyclic RORγt Inverse Agonists-Discovery of BMS-986313.
Yang, Michael G; Beaudoin-Bertrand, Myra; Xiao, Zili; Marcoux, David; Weigelt, Carolyn A; Yip, Shiuhang; Wu, Dauh-Rurng; Ruzanov, Max; Sack, John S; Wang, Jinhong; Yarde, Melissa; Li, Sha; Shuster, David J; Xie, Jenny H; Sherry, Tara; Obermeier, Mary T; Fura, Aberra; Stefanski, Kevin; Cornelius, Georgia; Khandelwal, Purnima; Karmakar, Ananta; Basha, Mushkin; Babu, Venkatesh; Gupta, Arun Kumar; Mathur, Arvind; Salter-Cid, Luisa; Denton, Rex; Zhao, Qihong; Dhar, T G Murali.
Affiliation
  • Yang MG; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Beaudoin-Bertrand M; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Xiao Z; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Marcoux D; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Weigelt CA; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Yip S; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Wu DR; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Ruzanov M; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Sack JS; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Wang J; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Yarde M; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Li S; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Shuster DJ; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Xie JH; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Sherry T; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Obermeier MT; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Fura A; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Stefanski K; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Cornelius G; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Khandelwal P; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Karmakar A; Department of Discovery Synthesis, Biocon Bristol-Myers Squibb Research Centre, Biocon Park, Bommasandra IV Phase, Jigani Link Road, Bengaluru 560099, India.
  • Basha M; Department of Discovery Synthesis, Biocon Bristol-Myers Squibb Research Centre, Biocon Park, Bommasandra IV Phase, Jigani Link Road, Bengaluru 560099, India.
  • Babu V; Department of Discovery Synthesis, Biocon Bristol-Myers Squibb Research Centre, Biocon Park, Bommasandra IV Phase, Jigani Link Road, Bengaluru 560099, India.
  • Gupta AK; Department of Discovery Synthesis, Biocon Bristol-Myers Squibb Research Centre, Biocon Park, Bommasandra IV Phase, Jigani Link Road, Bengaluru 560099, India.
  • Mathur A; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Salter-Cid L; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Denton R; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Zhao Q; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
  • Dhar TGM; Research and Early Development, Bristol Myers Squibb Company, Princeton, New Jersey 08543-4000, United States.
J Med Chem ; 64(5): 2714-2724, 2021 03 11.
Article in En | MEDLINE | ID: mdl-33591748
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Nuclear Receptor Subfamily 1, Group F, Member 3 / Amides / Hydrocarbons, Cyclic Limits: Animals / Female / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Nuclear Receptor Subfamily 1, Group F, Member 3 / Amides / Hydrocarbons, Cyclic Limits: Animals / Female / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States