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LRRK2 Ablation Attenuates Αlpha-Synuclein-Induced Neuroinflammation Without Affecting Neurodegeneration or Neuropathology In Vivo.
Van der Perren, Anke; Cabezudo, Diego; Gelders, Géraldine; Peralta Ramos, Javier M; Van den Haute, Chris; Baekelandt, Veerle; Lobbestael, Evy.
Affiliation
  • Van der Perren A; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 bus 1023, 3000, Leuven, Belgium.
  • Cabezudo D; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 bus 1023, 3000, Leuven, Belgium.
  • Gelders G; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 bus 1023, 3000, Leuven, Belgium.
  • Peralta Ramos JM; Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
  • Van den Haute C; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 bus 1023, 3000, Leuven, Belgium.
  • Baekelandt V; Leuven Viral Vector Core, KU Leuven, Leuven, Belgium.
  • Lobbestael E; Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 bus 1023, 3000, Leuven, Belgium. veerle.baekelandt@kuleuven.be.
Neurotherapeutics ; 18(2): 949-961, 2021 04.
Article in En | MEDLINE | ID: mdl-33594532
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Neurodegenerative Diseases / Alpha-Synuclein / Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / Neuroinflammatory Diseases / Indazoles Limits: Animals Language: En Journal: Neurotherapeutics Journal subject: NEUROLOGIA Year: 2021 Document type: Article Affiliation country: Belgium Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Neurodegenerative Diseases / Alpha-Synuclein / Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 / Neuroinflammatory Diseases / Indazoles Limits: Animals Language: En Journal: Neurotherapeutics Journal subject: NEUROLOGIA Year: 2021 Document type: Article Affiliation country: Belgium Country of publication: United States