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Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism.
Jensen, Benjamin A H; Holm, Jacob B; Larsen, Ida S; von Burg, Nicole; Derer, Stefanie; Sonne, Si B; Pærregaard, Simone I; Damgaard, Mads V; Indrelid, Stine A; Rivollier, Aymeric; Agrinier, Anne-Laure; Sulek, Karolina; Arnoldussen, Yke J; Fjære, Even; Marette, André; Angell, Inga L; Rudi, Knut; Treebak, Jonas T; Madsen, Lise; Åkesson, Caroline Piercey; Agace, William; Sina, Christian; Kleiveland, Charlotte R; Kristiansen, Karsten; Lea, Tor E.
Affiliation
  • Jensen BAH; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark. Benjamin.jensen@sund.ku.dk.
  • Holm JB; Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Laval, QC, Canada. Benjamin.jensen@sund.ku.dk.
  • Larsen IS; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Benjamin.jensen@sund.ku.dk.
  • von Burg N; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
  • Derer S; Clinical Microbiomics, Copenhagen, Denmark.
  • Sonne SB; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
  • Pærregaard SI; Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Laval, QC, Canada.
  • Damgaard MV; Mucosal Immunology, Department of Health Technology, Technical University of Denmark, Copenhagen, Denmark.
  • Indrelid SA; Institute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
  • Rivollier A; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
  • Agrinier AL; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
  • Sulek K; Mucosal Immunology, Department of Health Technology, Technical University of Denmark, Copenhagen, Denmark.
  • Arnoldussen YJ; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
  • Fjære E; Novo Nordisk Foundation Center for Basic Metabolic Research, Integrative Metabolism and Environmental Influences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Marette A; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Oslo, Norway.
  • Angell IL; Mucosal Immunology, Department of Health Technology, Technical University of Denmark, Copenhagen, Denmark.
  • Rudi K; Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Laval, QC, Canada.
  • Treebak JT; Novo Nordisk Foundation Center for Basic Metabolic Research, Integrative Metabolism and Environmental Influences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Madsen L; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Oslo, Norway.
  • Åkesson CP; Institute of Marine Research, Bergen, Norway.
  • Agace W; Department of Medicine, Faculty of Medicine, Cardiology Axis of the Québec Heart and Lung Institute, Laval University, Laval, QC, Canada.
  • Sina C; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Oslo, Norway.
  • Kleiveland CR; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Oslo, Norway.
  • Kristiansen K; Novo Nordisk Foundation Center for Basic Metabolic Research, Integrative Metabolism and Environmental Influences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Lea TE; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Nat Commun ; 12(1): 1093, 2021 02 17.
Article in En | MEDLINE | ID: mdl-33597537
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / T-Lymphocytes, Regulatory / Methylococcus capsulatus / Microbiota / Intestine, Large / Intestine, Small Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Denmark
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / T-Lymphocytes, Regulatory / Methylococcus capsulatus / Microbiota / Intestine, Large / Intestine, Small Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Document type: Article Affiliation country: Denmark