Inhibition of tumor invasion and metastasis by targeting TGF-ß-Smad-MMP2 pathway with Asiatic acid and Naringenin.

Lian, Guang-Yu; Wang, Qing-Ming; Mak, Thomas Shiu-Kwong; Huang, Xiao-Ru; Yu, Xue-Qing; Lan, Hui-Yao

Lian, Guang-Yu; Wang, Qing-Ming; Mak, Thomas Shiu-Kwong; Huang, Xiao-Ru; Yu, Xue-Qing; Lan, Hui-Yao.

Affiliation

Lian GY; Guangdong-Hong Kong Joint Research Laboratory on Immunological and Genetic Kidney Diseases, and Department of Pathology, Guangdong Academy of Medical Sciences, Guangdong Provincial People's Hospital, Guangzhou, China.
Wang QM; Department of Medicine and Therapeutics, and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Mak TS; Department of Medicine and Therapeutics, and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Huang XR; Department of Medicine and Therapeutics, and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Yu XQ; Guangdong-Hong Kong Joint Research Laboratory on Immunological and Genetic Kidney Diseases, and Department of Pathology, Guangdong Academy of Medical Sciences, Guangdong Provincial People's Hospital, Guangzhou, China.
Lan HY; Department of Medicine and Therapeutics, and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.

Mol Ther Oncolytics ; 20: 277-289, 2021 Mar 26.

Article in En | MEDLINE | ID: mdl-33614911

Key words

Asiatic acid and Naringenin; MMP2; Smad3; Smad7; TGF-ß; lung carcinoma; melanoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: Mol Ther Oncolytics Year: 2021 Document type: Article Affiliation country: China Country of publication: United States

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