Cell Biology: Resolving How DNA Is Damaged during 3D Migration.
Curr Biol
; 31(4): R209-R211, 2021 02 22.
Article
in En
| MEDLINE
| ID: mdl-33621513
ABSTRACT
Cells migrating through confined spaces are subject to mechanical stresses that can deform the nucleus and even rupture the nuclear envelope. A new study reveals that nuclear deformation is sufficient to trigger double-strand breaks at sites of active DNA replication.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cell Nucleus
/
Nuclear Envelope
Language:
En
Journal:
Curr Biol
Journal subject:
BIOLOGIA
Year:
2021
Document type:
Article