Prognostic Evaluation of the Site of Invasion in Pathological Stage T3a Renal Cell Carcinoma.
In Vivo
; 35(2): 1083-1089, 2021.
Article
in En
| MEDLINE
| ID: mdl-33622905
ABSTRACT
BACKGROUND/AIM:
To investigate the prognostic values of fat invasion (FI) and renal vein invasion (RVI) in pT3a renal cell carcinoma (RCC), as single factors or concomitant presence. PATIENTS ANDMETHODS:
We retrospectively reviewed the data of 173 patients who underwent radical or partial nephrectomy for RCC in our Institution.RESULTS:
At a median follow-up time of 48 months, patients with RVI showed significantly increased risk of disease recurrence and worse cancer-specific survival (CSS) when compared to those with FI (p=0.007, p=0.022, respectively). Having combined RVI and FI did not show inferior prognosis compared to those with RVI only. In multivariable analysis, RVI was an independent factor for disease recurrence (HR=2.06, 95% CI=1.10-3.87, p=0.024) and CSS (HR=2.46, 95% CI=1.01-6.0, p=0.048).CONCLUSION:
For patients with T3a renal tumors, RVI was associated with inferior prognosis compared to those with FI.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Carcinoma, Renal Cell
/
Kidney Neoplasms
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
In Vivo
Journal subject:
NEOPLASIAS
Year:
2021
Document type:
Article
Country of publication:
GR
/
GRECIA
/
GREECE
/
GRÉCIA