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An insight into the structure of 5-spiro aromatic derivatives of imidazolidine-2,4-dione, a new group of very potent inhibitors of tumor multidrug resistance in T-lymphoma cells.
Zeslawska, Ewa; Kucwaj-Brysz, Katarzyna; Kincses, Annamária; Spengler, Gabriella; Szymanska, Ewa; Czopek, Anna; Marc, Malgorzata Anna; Kaczor, Aneta; Nitek, Wojciech; Domínguez-Álvarez, Enrique; Latacz, Gniewomir; Kiec-Kononowicz, Katarzyna; Handzlik, Jadwiga.
Affiliation
  • Zeslawska E; Institute of Biology, Pedagogical University, Podchorazych 2, 30-084 Kraków, Poland.
  • Kucwaj-Brysz K; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
  • Kincses A; Department of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
  • Spengler G; Department of Medical Microbiology and Immunobiology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
  • Szymanska E; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
  • Czopek A; Department of Medicinal Chemistry, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
  • Marc MA; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
  • Kaczor A; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
  • Nitek W; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kraków, Poland.
  • Domínguez-Álvarez E; Instituto de Química Orgánica General, Consejo Superior de Investigaciones Científicas (IQOG-CSIC), Juan de la Cierva 3, 28006, Madrid, Spain.
  • Latacz G; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
  • Kiec-Kononowicz K; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
  • Handzlik J; Department of Technology and Biotechnology of Drugs, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland. Electronic address: j.handzlik@uj.edu.pl.
Bioorg Chem ; 109: 104735, 2021 04.
Article in En | MEDLINE | ID: mdl-33640632

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spiro Compounds / Lymphoma, T-Cell / Imidazolidines / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2021 Document type: Article Affiliation country: Poland Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spiro Compounds / Lymphoma, T-Cell / Imidazolidines / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Chem Year: 2021 Document type: Article Affiliation country: Poland Country of publication: United States