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Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline.
Villafraz, Oriana; Biran, Marc; Pineda, Erika; Plazolles, Nicolas; Cahoreau, Edern; Ornitz Oliveira Souza, Rodolpho; Thonnus, Magali; Allmann, Stefan; Tetaud, Emmanuel; Rivière, Loïc; Silber, Ariel M; Barrett, Michael P; Zíková, Alena; Boshart, Michael; Portais, Jean-Charles; Bringaud, Frédéric.
Affiliation
  • Villafraz O; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
  • Biran M; Univ. Bordeaux, CNRS, Centre de Résonance Magnétique des Systèmes Biologiques (CRMSB), UMR 5536, Bordeaux, France.
  • Pineda E; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
  • Plazolles N; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
  • Cahoreau E; Toulouse Biotechnology Institute, TBI-INSA de Toulouse INSA/CNRS 5504-UMR INSA/INRA 792, Toulouse, France.
  • Ornitz Oliveira Souza R; MetaToul-MetaboHub, National Infrastructure of Metabolomics and Fluxomics, Toulouse, France.
  • Thonnus M; Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Allmann S; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
  • Tetaud E; Fakultät für Biologie, Genetik, Ludwig-Maximilians-Universität München, Grosshadernerstrasse 2-4, Martinsried, Germany.
  • Rivière L; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
  • Silber AM; Univ. Bordeaux, CNRS, Microbiologie Fondamentale et Pathogénicité (MFP), UMR 5234, Bordeaux, France.
  • Barrett MP; Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Zíková A; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Boshart M; Glasgow Polyomics, Wolfson Wohl Cancer Research Centre, Garscube Campus, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
  • Portais JC; Institute of Parasitology, Biology Center, Czech Academy of Sciences, Ceské Budejovice, Czech Republic.
  • Bringaud F; Fakultät für Biologie, Genetik, Ludwig-Maximilians-Universität München, Grosshadernerstrasse 2-4, Martinsried, Germany.
PLoS Pathog ; 17(3): e1009204, 2021 03.
Article in En | MEDLINE | ID: mdl-33647053
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanosoma / Trypanosoma brucei brucei / Proline / Tsetse Flies / Glucose Limits: Animals Language: En Journal: PLoS Pathog Year: 2021 Document type: Article Affiliation country: France Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trypanosoma / Trypanosoma brucei brucei / Proline / Tsetse Flies / Glucose Limits: Animals Language: En Journal: PLoS Pathog Year: 2021 Document type: Article Affiliation country: France Country of publication: United States