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Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line.
Gu, Chunfang; Liu, Juan; Liu, Xiaojing; Zhang, Haibo; Luo, Ji; Wang, Huanchen; Locasale, Jason W; Shears, Stephen B.
Affiliation
  • Gu C; Signal Transduction Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709; guc2@nih.gov.
  • Liu J; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710.
  • Liu X; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710.
  • Zhang H; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892.
  • Luo J; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892.
  • Wang H; Signal Transduction Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709.
  • Locasale JW; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710.
  • Shears SB; Signal Transduction Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709.
Proc Natl Acad Sci U S A ; 118(10)2021 03 09.
Article in En | MEDLINE | ID: mdl-33649228
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Phosphotransferases (Phosphate Group Acceptor) / Colonic Neoplasms / Cell Proliferation / Carcinogenesis / Neoplasm Proteins Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Phosphotransferases (Phosphate Group Acceptor) / Colonic Neoplasms / Cell Proliferation / Carcinogenesis / Neoplasm Proteins Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article Country of publication: United States