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MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity.
Branigan, Timothy B; Kozono, David; Schade, Amy E; Deraska, Peter; Rivas, Hembly G; Sambel, Larissa; Reavis, Hunter D; Shapiro, Geoffrey I; D'Andrea, Alan D; DeCaprio, James A.
Affiliation
  • Branigan TB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Program in Virology, Graduate School of Arts and Sciences, Harvard University, Cambridge, MA, USA.
  • Kozono D; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Schade AE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Program in Virology, Graduate School of Arts and Sciences, Harvard University, Cambridge, MA, USA.
  • Deraska P; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Rivas HG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Program in Virology, Graduate School of Arts and Sciences, Harvard University, Cambridge, MA, USA.
  • Sambel L; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Reavis HD; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Shapiro GI; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • D'Andrea AD; Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • DeCaprio JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Program in Virology, Graduate School of Arts and Sciences, Harvard University, Cambridge, MA, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic a
Cell Rep ; 34(9): 108808, 2021 03 02.
Article in En | MEDLINE | ID: mdl-33657372

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazines / Pyrazoles / Trans-Activators / Carcinoma, Non-Small-Cell Lung / Cell Cycle Proteins / Protein Kinase Inhibitors / Checkpoint Kinase 1 / Forkhead Box Protein M1 / Lung Neoplasms / Mitosis Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Cell Rep Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazines / Pyrazoles / Trans-Activators / Carcinoma, Non-Small-Cell Lung / Cell Cycle Proteins / Protein Kinase Inhibitors / Checkpoint Kinase 1 / Forkhead Box Protein M1 / Lung Neoplasms / Mitosis Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Cell Rep Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States