Hypoglycemia Due to Acquired Carnitine Deficiency in a Pediatric Patient Receiving Chemotherapy.
J Pediatr Hematol Oncol
; 44(2): e496-e499, 2022 Mar 01.
Article
in En
| MEDLINE
| ID: mdl-33661167
ABSTRACT
We describe a 21-month-old male with relapsed clear cell sarcoma of the kidney receiving enteral nutrition who experienced recurrent, ketotic hypoglycemia. During relapse therapy, he had recurrent hypoglycemia episodes, in the setting of hematochezia and diarrhea. Evaluation revealed low carnitine levels. He received supplementation with oral levocarnitine throughout the remainder of treatment, resulting in normalization of serum carnitine levels and no further hypoglycemia. We believe adverse effects of the chemotherapy on his single kidney and gastrointestinal insult resulted in hypoglycemia and carnitine deficiency. Our case highlights that carnitine deficiency should be considered when acute onset hypoglycemia without obvious cause occurs.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Hyperammonemia
/
Malnutrition
/
Hypoglycemia
/
Cardiomyopathies
Aspects:
Determinantes_sociais_saude
Limits:
Child
/
Humans
/
Infant
/
Male
Language:
En
Journal:
J Pediatr Hematol Oncol
Journal subject:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Year:
2022
Document type:
Article