Your browser doesn't support javascript.
loading
Treatment of Relapsed and Refractory ALK-Positive Anaplastic Large Cell Lymphoma With ALK-Specific Tyrosine Kinase Inhibitor in Children: A Case Series.
Shen, Diying; Song, Hua; Zhang, Jingying; Liao, Chan; Wang, Yan; Fang, Meixin; Tang, Yongmin.
Affiliation
  • Shen D; Department of Hematology and Oncology, Pediatric Hematology-Oncology Center, Pediatric Leukemia Diagnosis and Therapeutic Technology Research Center of Zhejiang Province, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
J Pediatr Hematol Oncol ; 44(1): e1-e4, 2022 01 01.
Article in En | MEDLINE | ID: mdl-33661174
ABSTRACT
Relapsed and refractory ALK-positive anaplastic large cell lymphoma (ALCL) has a poor prognosis. In this report, we present 3 relapsed/refractory pediatric ALCL patients, 1 of these with central nervous system involvement. All 3 patients were treated with ALK inhibitor and achieved complete response. Both crizotinib and alectinib have shown significant activity in pediatric patients with refractory ALK-positive ALCL.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Carbazoles / Lymphoma, Large-Cell, Anaplastic / Crizotinib / Anaplastic Lymphoma Kinase / Neoplasm Proteins Type of study: Prognostic_studies Limits: Child / Female / Humans / Infant Language: En Journal: J Pediatr Hematol Oncol Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2022 Document type: Article Affiliation country: China
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Carbazoles / Lymphoma, Large-Cell, Anaplastic / Crizotinib / Anaplastic Lymphoma Kinase / Neoplasm Proteins Type of study: Prognostic_studies Limits: Child / Female / Humans / Infant Language: En Journal: J Pediatr Hematol Oncol Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2022 Document type: Article Affiliation country: China