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Oligomeric Aß1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function.
Lynn, Savannah A; Johnston, David A; Scott, Jenny A; Munday, Rosie; Desai, Roshni S; Keeling, Eloise; Weaterton, Ruaridh; Simpson, Alexander; Davis, Dillon; Freeman, Thomas; Chatelet, David S; Page, Anton; Cree, Angela J; Lee, Helena; Newman, Tracey A; Lotery, Andrew J; Ratnayaka, J Arjuna.
Affiliation
  • Lynn SA; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Johnston DA; Biomedical Imaging Unit, University of Southampton, MP12, Tremona Road, Southampton SO16 6YD, UK.
  • Scott JA; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Munday R; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Desai RS; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Keeling E; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Weaterton R; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Simpson A; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Davis D; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Freeman T; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Chatelet DS; Biomedical Imaging Unit, University of Southampton, MP12, Tremona Road, Southampton SO16 6YD, UK.
  • Page A; Biomedical Imaging Unit, University of Southampton, MP12, Tremona Road, Southampton SO16 6YD, UK.
  • Cree AJ; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Lee H; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Newman TA; Eye Unit, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.
  • Lotery AJ; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
  • Ratnayaka JA; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, MP 806, Tremona Road, Southampton SO16 6YD, UK.
Cells ; 10(2)2021 02 17.
Article in En | MEDLINE | ID: mdl-33671133

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Phenotype / Amyloid beta-Peptides / Lysosomes / Macular Degeneration Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cells Year: 2021 Document type: Article Affiliation country: United kingdom Country of publication: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Phenotype / Amyloid beta-Peptides / Lysosomes / Macular Degeneration Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cells Year: 2021 Document type: Article Affiliation country: United kingdom Country of publication: Switzerland