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Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2.
Baggen, Jim; Persoons, Leentje; Vanstreels, Els; Jansen, Sander; Van Looveren, Dominique; Boeckx, Bram; Geudens, Vincent; De Man, Julie; Jochmans, Dirk; Wauters, Joost; Wauters, Els; Vanaudenaerde, Bart M; Lambrechts, Diether; Neyts, Johan; Dallmeier, Kai; Thibaut, Hendrik Jan; Jacquemyn, Maarten; Maes, Piet; Daelemans, Dirk.
Affiliation
  • Baggen J; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium. jim.baggen@kuleuven.be.
  • Persoons L; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Vanstreels E; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Jansen S; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Van Looveren D; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Boeckx B; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Translational Platform Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Geudens V; KU Leuven Department of Human Genetics, Laboratory for Translational Genetics, Leuven, Belgium.
  • De Man J; VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Jochmans D; KU Leuven Department of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Leuven, Belgium.
  • Wauters J; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Wauters E; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Vanaudenaerde BM; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical Infectious and Inflammatory Disorders, Leuven, Belgium.
  • Lambrechts D; KU Leuven Department of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Leuven, Belgium.
  • Neyts J; KU Leuven Department of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Leuven, Belgium.
  • Dallmeier K; KU Leuven Department of Human Genetics, Laboratory for Translational Genetics, Leuven, Belgium.
  • Thibaut HJ; VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Jacquemyn M; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Maes P; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
  • Daelemans D; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, Leuven, Belgium.
Nat Genet ; 53(4): 435-444, 2021 04.
Article in En | MEDLINE | ID: mdl-33686287
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome, Human / Genome-Wide Association Study / CRISPR-Cas Systems / COVID-19 / Membrane Proteins / Nerve Tissue Proteins Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2021 Document type: Article Affiliation country: Belgium Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome, Human / Genome-Wide Association Study / CRISPR-Cas Systems / COVID-19 / Membrane Proteins / Nerve Tissue Proteins Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2021 Document type: Article Affiliation country: Belgium Country of publication: United States