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Cell metabolomics analyses revealed a role of altered fatty acid oxidation in neurotoxicity pattern difference between nab-paclitaxel and solvent-based paclitaxel.
Huang, Jhih-Wei; Kuo, Ching-Hua; Kuo, Han-Chun; Shih, Jin-Yuan; Tsai, Teng-Wen; Chang, Lin-Chau.
Affiliation
  • Huang JW; School of Pharmacy, College of Medicine, National Taiwan University, Taipei City, Zhongzheng Dist., Taiwan.
  • Kuo CH; School of Pharmacy, College of Medicine, National Taiwan University, Taipei City, Zhongzheng Dist., Taiwan.
  • Kuo HC; The Metabolomics Core Laboratory, Centers of Genomic and Precision Medicine, National Taiwan University, Taipei City, Zhongzheng Dist., Taiwan.
  • Shih JY; The Metabolomics Core Laboratory, Centers of Genomic and Precision Medicine, National Taiwan University, Taipei City, Zhongzheng Dist., Taiwan.
  • Tsai TW; Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Zhongzheng Dist., Taiwan.
  • Chang LC; School of Pharmacy, College of Medicine, National Taiwan University, Taipei City, Zhongzheng Dist., Taiwan.
PLoS One ; 16(3): e0248942, 2021.
Article in En | MEDLINE | ID: mdl-33740022

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Solvents / Paclitaxel / Albumins / Fatty Acids / Metabolomics / Neurotoxins Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2021 Document type: Article Affiliation country: Taiwan Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Solvents / Paclitaxel / Albumins / Fatty Acids / Metabolomics / Neurotoxins Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2021 Document type: Article Affiliation country: Taiwan Country of publication: United States