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Standard protocol for the PIGRET assay, a high-throughput reticulocyte Pig-a assay with an immunomagnetic separation, used in the interlaboratory trial organized by the Mammalian Mutagenicity Study Group of the Japanese Environmental Mutagen and Genome Society.
Chikura, Satsuki; Kimoto, Takafumi; Itoh, Satoru; Sanada, Hisakazu; Muto, Shigeharu; Horibata, Katsuyoshi.
Affiliation
  • Chikura S; Toxicology Research Department, Teijin Institute for Bio-medical Research, Teijin Pharma Limited, 4-3-2 Asahigaoka, Hino-shi, Tokyo, 191-8512, Japan.
  • Kimoto T; Toxicology Research Department, Teijin Institute for Bio-medical Research, Teijin Pharma Limited, 4-3-2 Asahigaoka, Hino-shi, Tokyo, 191-8512, Japan. t.kimoto@teijin.co.jp.
  • Itoh S; Medicinal Safety Research Laboratories, Daiichi Sankyo Co., Ltd., 1-16-13, Kitakasai, Edogawa-ku, Tokyo, 134-8630, Japan.
  • Sanada H; Development ADMET Department, Translational Research Division, Chugai Pharmaceutical Co., Ltd., 1-135 Komakado, Gotemba-shi, 412-8513, Japan.
  • Muto S; Safety Research Laboratories, Mitsubishi Tanabe Pharma Corporation, Shonan Health Innovation Park, 2-26-1, Muraoka-Higashi, Fujisawa, Kanagawa, 251-8555, Japan.
  • Horibata K; Division of Genetics and Mutagenesis, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan. horibata@nihs.go.jp.
Genes Environ ; 43(1): 10, 2021 Mar 20.
Article in En | MEDLINE | ID: mdl-33743813
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Guideline / Screening_studies Language: En Journal: Genes Environ Year: 2021 Document type: Article Affiliation country: Japan Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Guideline / Screening_studies Language: En Journal: Genes Environ Year: 2021 Document type: Article Affiliation country: Japan Country of publication: United kingdom