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Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains.
Renner, Daniel W; Parsons, Lance; Shreve, Jacob T; Engel, Esteban A; Kuny, Chad V; Enquist, Lynn; Neumann, Donna; Mangold, Colleen; Szpara, Moriah L.
Affiliation
  • Renner DW; Department of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.
  • Parsons L; Department of Biochemistry and Molecular Biology, Center for Infectious Disease Dynamics, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
  • Shreve JT; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA.
  • Engel EA; Department of Biochemistry and Molecular Biology, Center for Infectious Disease Dynamics, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
  • Kuny CV; Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, USA.
  • Enquist L; Department of Biology, Pennsylvania State University, University Park, Pennsylvania, USA.
  • Neumann D; Department of Biochemistry and Molecular Biology, Center for Infectious Disease Dynamics, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
  • Mangold C; Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.
  • Szpara ML; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Microbiol Resour Announc ; 10(12)2021 Mar 25.
Article in En | MEDLINE | ID: mdl-33766904
Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Microbiol Resour Announc Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Microbiol Resour Announc Year: 2021 Document type: Article Affiliation country: United States Country of publication: United States