Your browser doesn't support javascript.
loading
Dibenzyl trisulfide binds to and competitively inhibits the cytochrome P450 1A1 active site without impacting the expression of the aryl hydrocarbon receptor.
Wauchope, Shaniece; Roy, Monika A; Irvine, William; Morrison, Isaac; Brantley, Eileen; Gossell-Williams, Maxine; Timme-Laragy, Alicia R; Delgoda, Rupika.
Affiliation
  • Wauchope S; Natural Products Institute, University of the West Indies, Mona, Kingston 7, Jamaica.
  • Roy MA; Department of Environmental Health Sciences, University of Massachusetts Amherst, Amherst, MA 01003, USA.
  • Irvine W; Natural Products Institute, University of the West Indies, Mona, Kingston 7, Jamaica.
  • Morrison I; Natural Products Institute, University of the West Indies, Mona, Kingston 7, Jamaica.
  • Brantley E; Department of Basic Sciences, Center for Health Disparities and Molecular Medicine, Loma Linda University Health School of Medicine, Loma Linda, CA 92350, USA; Department of Pharmaceutical and Administrative Sciences, Loma Linda University Health School of Pharmacy, Loma Linda, CA 92350, USA.
  • Gossell-Williams M; Department of Basic Medical Sciences, University of the West Indies, Mona, Kingston 7, Jamaica.
  • Timme-Laragy AR; Department of Environmental Health Sciences, University of Massachusetts Amherst, Amherst, MA 01003, USA.
  • Delgoda R; Natural Products Institute, University of the West Indies, Mona, Kingston 7, Jamaica. Electronic address: thejani.delgoda@uwimona.edu.jm.
Toxicol Appl Pharmacol ; 419: 115502, 2021 05 15.
Article in En | MEDLINE | ID: mdl-33774063
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfides / Benzyl Compounds / Receptors, Aryl Hydrocarbon / Cytochrome P-450 CYP1A1 / Zebrafish Proteins / Cytochrome P-450 CYP1B1 / Cytochrome P-450 Enzyme Inhibitors Limits: Animals / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2021 Document type: Article Affiliation country: Jamaica Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfides / Benzyl Compounds / Receptors, Aryl Hydrocarbon / Cytochrome P-450 CYP1A1 / Zebrafish Proteins / Cytochrome P-450 CYP1B1 / Cytochrome P-450 Enzyme Inhibitors Limits: Animals / Humans Language: En Journal: Toxicol Appl Pharmacol Year: 2021 Document type: Article Affiliation country: Jamaica Country of publication: United States