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Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivo.
Huang, Hai; Park, Song; Zhang, Haibo; Park, Sijun; Kwon, Wookbong; Kim, Enugyung; Zhang, Xiujuan; Jang, Soyoung; Yoon, Duhak; Choi, Seong-Kyoon; Yi, Jun-Koo; Kim, Sung-Hyun; Dong, Zigang; Lee, Mee-Hyun; Ryoo, Zaeyoung; Kim, Myoung Ok.
Affiliation
  • Huang H; Department of Animal Science and Biotechnology, ITRD, Kyungpook National University, Sangju, 37224, Republic of Korea.
  • Park S; Core Protein Resources Center, DGIST, Daegu, Republic of Korea.
  • Zhang H; Department of Brain and Cognitive Sciences, DGIST, Daegu, Republic of Korea.
  • Park S; Department of Animal Science and Biotechnology, ITRD, Kyungpook National University, Sangju, 37224, Republic of Korea.
  • Kwon W; School of Life Science, Kyungpook National University, Daegu, Republic of Korea.
  • Kim E; Division of Biotechnology, DGIST, Daegu, Republic of Korea.
  • Zhang X; Department of Animal Science and Biotechnology, ITRD, Kyungpook National University, Sangju, 37224, Republic of Korea.
  • Jang S; Department of Pulmonary and Critical Care Medicine, Huashan Hospital, Fudan University, Shanghai, 200040, China.
  • Yoon D; School of Life Science, Kyungpook National University, Daegu, Republic of Korea.
  • Choi SK; Department of Animal Science and Biotechnology, ITRD, Kyungpook National University, Sangju, 37224, Republic of Korea.
  • Yi JK; Core Protein Resources Center, DGIST, Daegu, Republic of Korea.
  • Kim SH; Division of Biotechnology, DGIST, Daegu, Republic of Korea.
  • Dong Z; Gyeongsangbuk-do Livestock Research Institute, Yeongju, South Korea.
  • Lee MH; Department of Bio-Medical Analysis, Korea Polytechnic College, Chungnam, Korea.
  • Ryoo Z; China-US (Henan) Hormel Cancer Institute, Zhengzhou, 450008, Henan, China.
  • Kim MO; College of Korean Medicine, Dongshin University, Naju, Jeollanamdo, 58245, Republic of Korea. mhyun_lee@hanmail.net.
J Exp Clin Cancer Res ; 40(1): 114, 2021 Mar 30.
Article in En | MEDLINE | ID: mdl-33785035
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sesquiterpenes / Colorectal Neoplasms / Proto-Oncogene Proteins c-akt Limits: Animals / Female / Humans Language: En Journal: J Exp Clin Cancer Res Year: 2021 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sesquiterpenes / Colorectal Neoplasms / Proto-Oncogene Proteins c-akt Limits: Animals / Female / Humans Language: En Journal: J Exp Clin Cancer Res Year: 2021 Document type: Article Country of publication: United kingdom