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Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses.
Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I; Woods, Russell L; Bhowmick, Sabuj Chandra; Dohlman, Claes H; Espevik, Terje; Chodosh, James; Gonzalez-Andrades, Miguel; Mollnes, Tom Eirik.
Affiliation
  • Islam R; Department of Immunology, Oslo University Hospital and University of Oslo, Oslo, Norway. Electronic address: rakibul.lubikar@gmail.com.
  • Islam MM; Massachusetts Eye and Ear, Boston, MA, United States; Schepens Eye Research Institute, Boston, MA, United States; Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.
  • Nilsson PH; Department of Immunology, Oslo University Hospital and University of Oslo, Oslo, Norway; Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden; Department of Chemistry and Biomedicine, Linnaeus University, Kalmar, Sweden.
  • Mohlin C; Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden; Department of Chemistry and Biomedicine, Linnaeus University, Kalmar, Sweden.
  • Hagen KT; Department of Pathology, Oslo University Hospital/University of Oslo, Oslo, Norway.
  • Paschalis EI; Schepens Eye Research Institute, Boston, MA, United States; Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.
  • Woods RL; Schepens Eye Research Institute, Boston, MA, United States; Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.
  • Bhowmick SC; Department of Mathematics, University of Oslo, Oslo, Norway.
  • Dohlman CH; Massachusetts Eye and Ear, Boston, MA, United States; Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.
  • Espevik T; Centre of Molecular Inflammation Research, and Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Chodosh J; Massachusetts Eye and Ear, Boston, MA, United States; Department of Ophthalmology, Harvard Medical School, Boston, MA, United States.
  • Gonzalez-Andrades M; Massachusetts Eye and Ear, Boston, MA, United States; Schepens Eye Research Institute, Boston, MA, United States; Department of Ophthalmology, Harvard Medical School, Boston, MA, United States; Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Department of Ophthalmology, Reina Sofia Uni
  • Mollnes TE; Department of Immunology, Oslo University Hospital and University of Oslo, Oslo, Norway; Centre of Molecular Inflammation Research, and Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; Research Laboratory, Nordland Hospital, Bodo, Norw
Acta Biomater ; 127: 169-179, 2021 06.
Article in En | MEDLINE | ID: mdl-33785451
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Complement C5 / Corneal Transplantation / Lipopolysaccharide Receptors / Heterografts / Inflammation Limits: Animals / Humans Language: En Journal: Acta Biomater Year: 2021 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Complement C5 / Corneal Transplantation / Lipopolysaccharide Receptors / Heterografts / Inflammation Limits: Animals / Humans Language: En Journal: Acta Biomater Year: 2021 Document type: Article