Kainate receptors and synaptic plasticity.
Neuropharmacology
; 196: 108540, 2021 09 15.
Article
in En
| MEDLINE
| ID: mdl-33794245
ABSTRACT
Synaptic plasticity has classically been characterized to involve the NMDA and AMPA subtypes of glutamate receptors, with NMDA receptors providing the key trigger for the induction of long-term plasticity leading to changes in AMPA receptor expression. Here we review the more subtle roles played by kainate receptors, which contribute critical postsynaptic signalling as well as playing major presynaptic auto-receptor roles. We focus on two research areas plasticity of kainate receptors themselves and the contribution they make to the plasticity of synaptic transmission. This article is part of the special issue on Glutamate Receptors - Kainate receptors.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Receptors, Kainic Acid
/
Neuronal Plasticity
/
Neurons
Limits:
Animals
/
Humans
Language:
En
Journal:
Neuropharmacology
Year:
2021
Document type:
Article
Affiliation country:
United kingdom