Ficus erecta Thunb Leaves Alleviate Memory Loss Induced by Scopolamine in Mice via Regulation of Oxidative Stress and Cholinergic System.

Sohn, Eunjin; Kim, Yu Jin; Kim, Joo-Hwan; Jeong, Soo-Jin

Sohn, Eunjin; Kim, Yu Jin; Kim, Joo-Hwan; Jeong, Soo-Jin.

Affiliation

Sohn E; Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, 34054, South Korea. ssen4022@kiom.re.kr.
Kim YJ; Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, 34054, South Korea.
Kim JH; Department of Life Science, Gachon University, Seongnam, 21936, South Korea.
Jeong SJ; Clinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon, 34054, South Korea. sjijeong@kiom.re.kr.

Mol Neurobiol ; 58(8): 3665-3676, 2021 Aug.

Article in En | MEDLINE | ID: mdl-33797061

Subject(s)

Cholinergic Neurons/drug effects; Ficus; Memory Disorders/drug therapy; Oxidative Stress/drug effects; Plant Extracts/therapeutic use; Scopolamine/toxicity; Animals; Cell Line; Cholinergic Antagonists/toxicity; Cholinergic Neurons/metabolism; Dose-Response Relationship, Drug; Male; Memory Disorders/chemically induced; Memory Disorders/metabolism; Mice; Mice, Inbred ICR; Oxidative Stress/physiology; Plant Extracts/isolation & purification; Plant Extracts/pharmacology; Plant Leaves

Key words

Acetylcholinesterase; Ficus erecta Thunb leaf; Memory impairment; Neurodegenerative diseases; Nrf2/HO-1; Oxidative stress; Scopolamine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scopolamine / Plant Extracts / Oxidative Stress / Ficus / Cholinergic Neurons / Memory Disorders Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Neurobiol Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2021 Document type: Article Affiliation country: South Korea Country of publication: United States

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