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Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Pavia-Collado, Rubén; Cóppola-Segovia, Valentín; Miquel-Rio, Lluís; Alarcón-Aris, Diana; Rodríguez-Aller, Raquel; Torres-López, María; Paz, Verónica; Ruiz-Bronchal, Esther; Campa, Leticia; Artigas, Francesc; Montefeltro, Andrés; Revilla, Raquel; Bortolozzi, Analia.
Affiliation
  • Pavia-Collado R; Institut d'Investigacions Biomèdiques de Barcelona (IIBB), Spanish National Research Council (CSIC), 08036 Barcelona, Spain.
  • Cóppola-Segovia V; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
  • Miquel-Rio L; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII, 28029 Madrid, Spain.
  • Alarcón-Aris D; Laboratory of Neurobiology and Redox Pathology, Department of Basic Pathology, Federal University of Paraná (UFPR), Curitiba 81531-980, Brazil.
  • Rodríguez-Aller R; Institut d'Investigacions Biomèdiques de Barcelona (IIBB), Spanish National Research Council (CSIC), 08036 Barcelona, Spain.
  • Torres-López M; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
  • Paz V; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), ISCIII, 28029 Madrid, Spain.
  • Ruiz-Bronchal E; Institut d'Investigacions Biomèdiques de Barcelona (IIBB), Spanish National Research Council (CSIC), 08036 Barcelona, Spain.
  • Campa L; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
  • Artigas F; CHU de Quebec Research Center, Axe Neurosciences. Department of Molecular Medicine, Faculty of Medicine, Université Laval, Quebec City, QC G1V 4G2, Canada.
  • Montefeltro A; CERVO Brain Research Centre, Quebec City, QC G1J 2G3, Canada.
  • Revilla R; Institut d'Investigacions Biomèdiques de Barcelona (IIBB), Spanish National Research Council (CSIC), 08036 Barcelona, Spain.
  • Bortolozzi A; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Int J Mol Sci ; 22(6)2021 Mar 13.
Article in En | MEDLINE | ID: mdl-33805843
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Glycoconjugates / Oligonucleotides, Antisense / Point Mutation / Alpha-Synuclein Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Spain Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Glycoconjugates / Oligonucleotides, Antisense / Point Mutation / Alpha-Synuclein Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Spain Country of publication: Switzerland