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Accelerated Progression of Disseminated Coccidioidomycosis Following SARS-CoV-2 Infection: A Case Report.
Krauth, Daniel S; Jamros, Christina M; Rivard, Shayna C; Olson, Niels H; Maves, Ryan C.
Affiliation
  • Krauth DS; Division of Infectious Diseases, Naval Medical Center, San Diego, CA 92134, USA.
  • Jamros CM; Division of Infectious Diseases, Naval Medical Center, San Diego, CA 92134, USA.
  • Rivard SC; Department of Internal Medicine, US Naval Hospital, Tutuhan, GU 96910, USA.
  • Olson NH; Department of Dermatology, US Naval Hospital, Tutuhan, GU 96910, USA.
  • Maves RC; Department of Pathology, US Naval Hospital, Tutuhan, GU 96910, USA.
Mil Med ; 186(11-12): 1254-1256, 2021 11 02.
Article in En | MEDLINE | ID: mdl-33826724
ABSTRACT
We describe a patient with subclinical coccidioidomycosis who experienced rapid disease dissemination shortly after SARS-CoV-2 infection, suggesting host immune response dysregulation to coccidioidomycosis by SARS-CoV-2. We hypothesize that disrupted cell-mediated signaling may result after SARS-CoV-2 infection leading to functional exhaustion and CD8+ T-cell senescence with impairment in host cellular response to Coccidioides infection.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coccidioidomycosis / COVID-19 Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Mil Med Year: 2021 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coccidioidomycosis / COVID-19 Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Mil Med Year: 2021 Document type: Article Affiliation country: United States