Sensitive protein alignments at tree-of-life scale using DIAMOND.
Nat Methods
; 18(4): 366-368, 2021 04.
Article
in En
| MEDLINE
| ID: mdl-33828273
ABSTRACT
We are at the beginning of a genomic revolution in which all known species are planned to be sequenced. Accessing such data for comparative analyses is crucial in this new age of data-driven biology. Here, we introduce an improved version of DIAMOND that greatly exceeds previous search performances and harnesses supercomputing to perform tree-of-life scale protein alignments in hours, while matching the sensitivity of the gold standard BLASTP.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Proteins
/
Sequence Alignment
/
Computational Biology
Type of study:
Diagnostic_studies
Language:
En
Journal:
Nat Methods
Journal subject:
TECNICAS E PROCEDIMENTOS DE LABORATORIO
Year:
2021
Document type:
Article
Affiliation country:
Germany