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Repeated mutation of a developmental enhancer contributed to human thermoregulatory evolution.
Aldea, Daniel; Atsuta, Yuji; Kokalari, Blerina; Schaffner, Stephen F; Prasasya, Rexxi D; Aharoni, Adam; Dingwall, Heather L; Warder, Bailey; Kamberov, Yana G.
Affiliation
  • Aldea D; Department of Genetics, Perelman School of Medicine, Philadelphia, PA 19104.
  • Atsuta Y; Genetics Department, Harvard Medical School, Boston, MA 02115.
  • Kokalari B; Department of Genetics, Perelman School of Medicine, Philadelphia, PA 19104.
  • Schaffner SF; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02138.
  • Prasasya RD; Epigenetics Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, Philadelphia, PA 19104.
  • Aharoni A; Department of Genetics, Perelman School of Medicine, Philadelphia, PA 19104.
  • Dingwall HL; Department of Genetics, Perelman School of Medicine, Philadelphia, PA 19104.
  • Warder B; Department of Genetics, Perelman School of Medicine, Philadelphia, PA 19104.
  • Kamberov YG; Department of Genetics, Perelman School of Medicine, Philadelphia, PA 19104; yana2@pennmedicine.upenn.edu.
Proc Natl Acad Sci U S A ; 118(16)2021 04 20.
Article in En | MEDLINE | ID: mdl-33850016

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Body Temperature Regulation / Homeodomain Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Body Temperature Regulation / Homeodomain Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Document type: Article Country of publication: United States